Planet earth: a corporate laboratory?
by Anna Pha According to George Lawton, writing in "Acres USA" (April 2001) the US Environmental Protection Agency was about to approve the release of a genetic engineered variant of Klepbsiella Planticola (KP), one of the most common bacteria on the planet, when a PhD student discovered that the genetically modified bacteria could put other plant life at risk. "The EPA had done a variety of tests on this organism, all of which indicated that it would not be toxic to humans or animals", said Mr Lawton. The EPA was not required to, and had not, tested the effects of the genetically engineered KP on plants. Mr Lawton reports that this particular variety of KP "had the unique ability to convert dead plant matter into alcohol. It was hoped that this would provide a way for farmers to transform their unused stalks, leaves and other type of compost material into alcohol, which could be used for washing, running vehicles, etc.". It was fortuitous that Michael Holmes, a student at the University of Oregon, had chosen to study the impact of KP on plants. Mr Holmes in his research found that all the plants in the soil with the genetically engineered KP had died as a result of the alcohol produced by the bacteria. Holmes notes that if genetically engineered KP had been released then it could have "colonised the entire planet over the course of several years, turning all of the soil where it grew into barren dirt". KP is found in the root systems of plants and in decomposing plant material around the world. If this particular variant of KP had been released then the question of recalling it would have been almost impossible. "Even plants pose a problem, despite the possibility of mechanical control. Imagine how hard it would be to selectively kill something that cannot be even seen with a naked eye", said Mr Lawton. "We have never been good at recapturing any organisms we have released into the world." The example of genetically engineered KP almost being released into the environment highlights the risks associated with genetic engineering of organisms and plants and the inadequacy of regulations and controls around the world to deal with them. Who knows what genetically modified organisms and plants have been released or where they were released. There have already been a number of serious accidents and escapes of genetically engineered agricultural products. The testing of these genetically modified (GM) plants is clearly inadequate. Accidents This is highlighted in a calendar of biotech calamities from just last year that was published by the Rural Advancement Foundation International (RAFI). RAFI's list of calamities includes a number of "accidents". "GM seeds were routinely — though accidentally — shipped to Europe by US and Canadian seed companies who couldn't seem to keep their conventional seeds separate from their GM lines", said RAFI. "In the following days, the sloppy inventory management problem spread throughout Western Europe as country after country found their fields contaminated with illegal and unwanted GM crops." The situation appears to be rapidly getting out of control. In New Zealand, the government admitted that there were at least 100 illicit GM crop experiments underway in that country. After checking half the experiments, the government decided that everything was OK. There was the StarLink debacle, where a GM maize variety banned in the US for human consumption because of fears of allergic reactions was permitted for use in feed for livestock. StarLink turned up in taco shells served at Taco Bell restaurants. Kellogs, the giant cereal company, had to close down one plant fearing that the illicit GM StarLink maize had infected its breakfast cereals. "In a panic, the White House sent emissaries to Japan and Europe to try to calm concerns that Aventis' StarLink had illegally entered their countries. Consumers joked that breakfast cereal makers would have to give away epi- needles or epi-pens (injections to treat anaphylactic shock) in cereal boxes instead of Power Rangers or Star War toys, for fear of allergic reactions in children", said RAFI. The StarLink maize also turned up in Japan and Korea. Another study confirmed that that the Bt toxin in transgenic maize could, contrary to industry expectations, escape into the soil killing larvae up to 25 days after the break-out. The impossible Apart from the big corporations like Monsanto and Aventis being beyond the control of governments, these corporations themselves do not have complete control of what they are producing. The unexpected or the impossible occurs from time to time. There is for example a case of the "jumping gene". This is where genetic changes cross species. One researcher found that a gene had transferred from genetically engineered rapeseed to bacteria and fungi discovered in the gut of honeybees. The industry had previously claimed such a transfer was highly unlikely or impossible. One large-scale study in Britain found that crosses can occur between GM herbicide-tolerant crops and weeds. In Germany researchers reported that sugarbeet designed to resist one herbicide accidentally acquired resistance to a second herbicide raising fears of the possibility of gene diffusion into weeds and the creation of superweeds. These examples are just a few of the calamities that occurred in the bio- tech industry. It is not surprising that the public is becoming more and more wary and concerned about GM products and are demanding stricter controls and labelling of food. The industry is feeling the heat in some areas as the public resist, where they are aware, GM products. In the US maize growers are now shunning GM seeds because their 1998/99 exports to Europe dropped from two million tonnes a year earlier to only 137,000 tonnes. Major potato processors and fast-food chains are also now warning growers to avoid GM potatoes. RAFI reports that the first meeting of the UN Food and Agriculture Organisation's Ethics Panel, a group of world renowned agronomists and ethicists, concluded that GM crops are risky, terminator technology is immoral, and patenting genes and other genetic material leads to crop genetic erosion and unacceptable monopoly. "In essence, the $2.5 billion GM seed market involves four major industrial crops (soybean, maize, cotton and canola) grown in three countries (the US, Argentina and Canada accounted for 98 per cent of the total GM area in 2000)", said RAFI. "In 1999, Monsanto GM seed traits accounted for over four-fifth of the total world area devoted to GM crops." These corporations see bio-safety in terms of safeguarding their monopoly rights over plants, seeds and food and safeguarding their profits. The risks that these corporations are prepared to take in pursuit of profits can be seen in their preparedness to release the inadequately tested genetically engineered variant of the KP bacteria. The lack of control and unpredictability of outcomes is illustrated by recent research findings by scientists at Australia's Co-Operative Research Centre for Biological Control of Pest Animals Canberra (CRC). The CRC uses biotechnology to develop means for controlling the fertility of pest animals such as mice, rats, rabbits and foxes. Rats and mice destroy billions of dollars worth of grain harvests around the world each year. This particular research involves the modification of a mousepox virus to include a gene which affects the immune system. The aim was to cause an immune response to its own reproductive cells — making the animal infertile. The results were unexpected. The new virus turned out to be a killer — all the mice involved died. Doctor Annabelle Duncan at Australia's Commonwealth Scientific and Industrial Research Organisation (CSIRO) asks: "Could a similar experiment be conducted on a human disease-causing organism with similar results? If so, could this be exploited by an unscrupulous nation or a bioterrorist to develop biological weapons? "The answer to the first question is that we simply do not know. There is no way of extrapolating from these results to another virus and another host animal. All we can say is that it is theoretically possible." The genetic modifications not only turned a mild virus into a deadly one it also proved resistant to attempts to vaccinate the mice. Up to now it has generally been believed that changes in the genetic make up of viruses made them less virulent, not more as in this case. There are equally unpredictable and uncontrollable outcomes when plants are genetically modified. No one knows what the nutritional value will be with the new products and whether they'll be harmful to people or the environment. And who knows what future generations of these plants will bring: the transgenic DNA is proving to be structurally unstable leading to random effects in subsequent generations. Gene transfer between species is also an unknown element. For example, pollen from a genetically modified rapeseed that was tolerant to a particular herbicide was fed to immature bee larvae. When various microorganisms were taken from the gut of the larvae and examined it was found that some of the bacteria as well as yeast cells had become resistant to that particular herbicide as well. "There are fundamental deficiencies in the science and technology of genetic manipulation, and, accordingly, basic flaws in existing regulatory systems. "This is especially the case with the major exporting producers, such as the US and Canada. These two factors, combined with the commercial self- interest of the biotechnology industry, are making us the largest laboratory in history — both in human and in biodiversity terms", warns Third World Resurgence. "Commercial pressure is so dominant that sound science is being subverted and government oversight eroded. Cases of suppression of scientific dissent are now reported. Entire arms of public universities are being taken over by corporations and it is alarming that the obvious conflict of interests has largely gone unquestioned." The attempt in Seattle (at the third Ministerial Conference of the World Trade Organisation) by the US, Canada and Japan to convert the safety issue of GE agricultural products into a predominantly trade issue in the WTO is a grim reminder of the power of industry. "Enough Southern governments realised the danger of that move, and successfully defeated it, supported by some European environment ministers", said Third World Resurgence. The Cartagena protocol on biosafety, which, was concluded in February 2000 despite considerable opposition from the US, Canada and Australia, is an important step forward in biosafety regulation. It is important that countries sign the protocol and take steps to legislate for minimum standards. Time is running out as supermarkets are being flooded by genetically engineered products, in the main without public or government knowledge. The resistance to these products and public consciousness of the issues is on the rise worldwide. There are many calls from scientists and NGOs around the world for a strengthening of the international protocol and for a moratorium on research and production of genetically modified products. Third World Resurgence warns:"Until effective international biosafety regulation and national biosafety regulation and capacity are established, there should be: a global moratorium on trans-boundary movements of GE seeds and other GE material; compulsory labelling of products without thresholds on the engineered DNA or protein present; and liability legally conferred on corporate producers and not on small or family farmers bearing the burden of crop failures or environmental/health damage." It is far easier to prevent mistakes than to withdraw mistakes from nature.